Immersion, Hyperoxia, Hypercapnia: Additive Effect Upon Pulmonary Function

Paper #:
  • 941261

Published:
  • 1994-06-01
Citation:
Tikhonov, M., Baranov, V., and Kotov, A., "Immersion, Hyperoxia, Hypercapnia: Additive Effect Upon Pulmonary Function," SAE Technical Paper 941261, 1994, https://doi.org/10.4271/941261.
Pages:
4
Abstract:
In a study of 6 men aged 29 to 48 we studied the effect of water body immersion during air or pure oxygen, or oxygen - 4 % CO2 gas mixture breathing upon pulmonary volumes and respiratory biomechanics (using bodyplethysmography), the extent of lung hydration (two-frequency impedansometry), and pulmonary metabolic function (by determination of the concentration of biologically active substances in the condensate of the exhaled air). We found an additive nature of immersion/hyperoxic effects upon the respiratory and metabolic pulmonary functions manifested in an acceleration and growth of a deficit in pulmonary vital capacity, a bronchoconstriction effect, increase of a lung hydration, and decrease of serotonin catabolism. Contrary to our expectation, we did non find any potentiation of oxygen induced toxic effects upon the lungs during immersion/hyperoxia/hypercapnia exposures.
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