A design of experiments is used to study the effect of laser weld parameters on formability of welded blanks for two different material combinations of cold rolled (bare) steel to cold rolled steel and cold rolled steel to hot dipped galvanized steel. Critical weld parameters influencing the formability of welded blanks are identified and the optimum weld set-up condition is obtained based on formability performance and consistency of formability for laser welded blanks. The results are applied to an automotive body side frame. The robustness of welded blank production is also assessed and the final welded set-up condition for the body side frame is obtained based on both the formability of welded blanks and the robustness of welded blank production. The body side frame is successfully made from the welded blanks with this final weld set-up condition. Part strain analysis for the body side frame is performed near the weld line and the results are compared to the forming limit of welded blanks.