Deformations of soft tissues and seat cushion foam are significant factors in determining the interface contours between the seat and the back of the thigh. This paper describes the measurement of forces, deformations, and contours of people's thighs and seat cushion materials. The goal of this work is to represent the human interactions with seats. A two-dimensional, plane strain finite element method was used to develop a contact model between the cross section of the human mid-thigh and flat surfaces, which can be a flat, rigid surface or a flat, foam cushion of various thicknesses and densities. Results of human and seat interactions for various subjects were measured, modeled, and compared. The present work showed a good agreement between experiments and models for various subjects and foam densities. The important results showed that the stiffness of the foam does not depend on the foam thickness.