The Trace Contaminant Control Subassembly (TCCS) to be used onboard the International Space Station (ISS) uses expendable adsorption beds and a conventional high temperature catalytic oxidizer to control trace chemical contaminants in the cabin air. Although effective, the current design has a high life cycle operating cost associated with maintaining the expendable beds and heating the catalytic oxidizer. In order to improve the TCCS's process economics, a retrofit to its primary design is being studied which utilizes an advanced technology lightweight, long-life Microlith™ catalytic converter (MCC). Development and testing of MCC prototypes for application to the TCCS have been conducted on a bench scale. Results from these studies are presented that show the converter's destruction performance for representative trace chemical contaminants found in a spacecraft cabin atmosphere.