This paper presents a model of Total Vehicle Vibration Isolation (TVVI) system for vibration analysis and optimization. The TVVI system can handle any number of flexible and rigid components, frequency independent and frequency dependent parameters of spring-damper subsystems, and considers motion with all six degrees of freedom. The modal mass, stiffness, and damping of the eigenvectors of finite-element (FE) model of the flexible components are included in the total vehicle model, instead of the original FE model. This procedure reduces the number of degree of freedom (DOF) of total vehicle model, so that the practical optimization including large FE model can be performed.Optimization module includes various options of objective functions (six kinds of energy and ride quality) for different design goals. Applications of TVVI include cars, buses trucks or any structure where NVH is an issue.