High mileage NVH performance is one of the major concerns in vehicle design for long term customer satisfaction. Elastomeric bushings and brake rotors are key chassis components which tend to degrade as vehicle mileage accumulates with time. The degradation of these components normally causes the overall degradation of vehicle NVH performance. In the current paper two categories of problems are addressed respectively: road-induced vibration due to bushing degradation, and brake roughness due to rotor wear. A system integration approach is used to derive the design strategies that can potentially make the vehicle more robust in these two NVH attributes. The approach links together bushing degradation characteristics, brake rotor wear characteristics, the design of experiment (DOE) method, and CAE modeling in a systematic fashion. The concept and method are demonstrated using a production vehicle.